From The Guardian: “I began to feel that myself plus the bicycle equaled myself plus the world,” said American women’s suffragist Frances Willard in the 1800s, epitomising how bicycles were caught up with women’s rights and social reform in the US. Back then the image of a woman on a set of wheels symbolised a swelling tide of transportation independence and freedom from restrictive Victorian fashion for women. Fast forward a century later, halfway across the world in the Indian state of Bihar, and a similar revolution is afoot. Bicycles gifted by the state government are teaching families that their girls can move around fearlessly, attend school like their brother and act on their ambitions, untethered to cultural expectations of their role in society.”
The weight-loss drug Ozempic was derived from the venom of the Gila monster lizard
From The University of Queensland: “In the 1980s John Pisano, a biochemist with a penchant for venoms, and a young gastroenterologist Jean-Pierre Raufman were working with poisonous lizard venom from the Gila monster, a slow-moving reptile native to the south of the United States and north of Mexico. By the 1990s, Pisano, Raufman and colleague John Eng identified a hormone-like molecule they called exendin-4. This stimulated insulin secretion via action at the same receptor as GLP-1. Excitingly, exendin-4 was not quickly metabolised by the body, and so might be useful as a diabetic therapeutic. Eng was convinced this would work, but pharmaceutical companies didn’t want to give people a hormone that would mimic a drug from a venomous lizard. Even the medical centre where Eng was working said that it wouldn’t help fill the patent.”
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