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One procedure has enabled the births of more than 10 million babies around the world, and nearly 3 percent of United States births per year — and it only became available relatively recently. People have had children via in vitro fertilization, or IVF, since 1978, though it took around a decade for the technique to become more widely accessible. Boston-based physician John Rock was the first to test the technique with human eggs. Lab technician Miriam Menkin assisted him by extracting eggs from ovaries removed from hysterectomy patients. She put these eggs in solution, cultured them, and added sperm in a petri dish. Over nearly six years, she attempted to fertilize more than 100 eggs without success. Finally, in February 1944, she saw success after increasing the contact between the sperm and egg from 30 minutes to an hour — an accidental adjustment because she, the mother of an infant, had fallen asleep during the experiment. (via Nautilus)

Some people are literally allergic to the cold and it can kill them if they are unprepared

It’s safe to say that most people don’t love the cold weather. It’s uncomfortable, you need to wear layers, and the bite in the air can physically hurt. But for some people, cold weather could actually kill them. There’s a real medical condition behind that sentence, and it’s called cold urticaria. It’s a rare disorder where exposure to cold temperatures causes the immune system to misfire. Instead of adapting to a temperature drop, the body reacts as if it’s under attack. Skin can erupt into hives. Swelling can spread across the whole body. Blood pressure can drop. In severe cases, the reaction escalates into anaphylaxis. Cold urticaria has been documented for centuries. Today, researchers know the condition affects about six out of every 10,000 people and appears nearly twice as often in women as in men. Symptoms usually begin in early adulthood, but children and older adults can develop the condition too. (via Vice)

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Continue reading “She paved the way for IVF technology by falling asleep”

Does an mini-Stonehenge stand underwater in Grand Traverse Bay, part of Lake Michigan? In 2007, looking for shipwrecks in this area, which was a busy 19th- and 20th-century maritime trade route, Mark Holley, professor of underwater archaeology at Northwestern Michigan University, first came across a rock that he said bears a prehistoric carving of a mastodon. On further investigation, he discovered a Stonehenge-like arrangement of ancient stones. There’s an outer ring of stones, about 40 feet in diameter, and an inner ring about 20 feet in diameter, both made of local granite. They stand 40 feet below the water’s surface, and the stones are some 9,000 years old. At that time, said Holley, the lake bed was dry. One theory is that it’s a smaller version of a prehistoric hunting structure found under Lake Huron, erected to herd caribou. (via ArtNet)

Napoleon’s brother Joseph left France and spent fifteen years living in New Jersey

Bonaparte trained as a lawyer. In that role and as a politician and diplomat, he served in the Council of Five Hundred and as the French ambassador to the Papal States. He was later crowned the king of Naples and Sicily after his brother conquered the region, and following that he became the king of Spain. Later, Bonaparte travelled to the United States onboard the Commerce under the name of M. Bouchard and arrived on 15 July 1815. Between 1817–1832, Bonaparte lived primarily in the United States (where he sold the jewels he had taken from Spain). He first settled in New York City and Philadelphia, where his house became the centre of activity for French emigres. In 1823, he was elected as a member to the American Philosophical Society. Later he purchased an estate, called Point Breeze, in Bordentown, New Jersey. (via Wikipedia)

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Continue reading “What is the Stonehenge-like structure in Lake Michigan?”

There is a memorable scene in “Oppenheimer,” the blockbuster film about the building of the atomic bomb, in which Luis Alvarez, a physicist at the University of California, Berkeley, is reading a newspaper while getting a haircut. Suddenly, Alvarez leaps from his seat and sprints down the road to find his colleague, the theoretical physicist J. Robert Oppenheimer.“Oppie! Oppie!” he shouts. “They’ve done it. Hahn and Strassmann in Germany. They split the uranium nucleus. They split the atom.”The reference is to two German chemists, Otto Hahn and Fritz Strassmann, who in 1939 unknowingly reported a demonstration of nuclear fission, the splintering of an atom into lighter elements. The discovery was key to the Manhattan Project, the top-secret American effort led by Oppenheimer to develop the first nuclear weapons.Except the scene is not entirely accurate. A major player is missing from the portrayal: Lise Meitner, a physicist who developed the theory of nuclear fission. (via the NYT)

Capitol Hill had a mystery soda machine with buttons that dispensed unusual flavors

The Capitol Hill mystery soda machine was a vending machine in Capitol Hill, Seattle, notable for its “mystery” buttons which dispensed unusual drink flavors. It is unknown who restocked the machine; this originally caused the development of a local legend that the machine was haunted. The machine reportedly operated from the late 1990s until its unexplained disappearance in 2018. It was located in front of Broadway Locksmith on East John Street in Seattle, Washington. It was a 1970s-made Coca-Cola-branded unit, but dispensed drinks from various manufacturers. A drink could be ordered using one of the “mystery” buttons and some of the dispensed drinks were unusual varieties which were no longer being manufactured. Broadway Locksmith provided electricity to power the machine but employees said they didn’t stock the machine. (via Wikipedia)

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Continue reading “The mother of the atomic bomb who never won a Nobel Prize”

A team of doctors working at the University of Munich reported the unusual case of a young man who experiences epileptic seizures every time he tries to solve a sudoku puzzle. The 25-year-old right-handed physical education student was buried in an avalanche during a skiing holiday, as a result of which his brain was deprived of oxygen for some 15 minutes. He then developed shock-like contractions of the muscles in his mouth when he tried to talk, and in his legs when he tried to walk. Several weeks later, while trying to solve Sudoku puzzles, he developed clonic seizures in his left arm. These produce repeated jerking movements, and are far rarer than tonic-clonic seizures, which are typically preceded by muscle stiffness, and cause a total loss of consciousness. In this case, the seizures stopped immediately when the patient stopped solving the Sudoku puzzle. He didn’t experience any seizures when he read a book, wrote something down, or did calculations. (via The Guardian)

An ancient fingerprint is among the clues to a 2,000-year-old invasion of Denmark

More than 2,000 years ago, a mysterious band of attackers descended on an island called Als off Denmark’s coast. Locals seem to have successfully fought back against the marauders and dumped one of their boats—chock-full of weapons—into a bog to celebrate their defeat of the invaders. Remnants of this ancient battle were unearthed in the 1880s by people digging for peat in the Hjortspring bog on Als. Researchers excavated the invaders’ boat in the 1920s and recovered nearly half of it, which provided enough material for a full reconstruction. This ancient wooden plank boat is the only intact vessel of its kind ever discovered in Scandinavia, and it resembles boats depicted around a millennium earlier in Bronze Age rock art. The bog boat still begs a major question: Where did the invaders actually invade from, and when? (via Nautilus)

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Continue reading “He experiences seizures but only while doing a Sudoku”

On the evening of 3 December 1926 the couple fought and Archie left their home to spend a weekend away with friends, including his mistress. Agatha departed the house later that same evening. The next morning her abandoned car was found several miles away partly submerged in bushes. The fact that the driver was missing but the headlights were on and a suitcase and coat remained in the back seat only fuelled the mystery. A huge manhunt was undertaken by thousands of policemen and eager volunteers, and a local lake known as the Silent Pool was also dredged. Home Secretary William Joynson-Hicks put pressure on police to find the writer, and Sir Arthur Conan Doyle sought the help of a clairvoyant to find Agatha. Ten days later, the head waiter at a hotel in Yorkshire contacted police with the startling news that a guest by the name of Theresa Neale might actually be the missing writer in disguise. (via Historic UK)

Christopher Nolan’s brother was charged with murder while using the name Oppenheimer

Sometimes life can be stranger than fiction, and that appeared to be the case with a bizarre rumor that movie director Christopher Nolan’s brother was a hitman using the codename “Oppenheimer.” In 2009, Matthew Nolan was arrested and charged with the murder of accountant Robert Cohen in Costa Rica. Costa Rica unsuccessfully applied for Nolan to be extradited from the United States in 2009. In their records, they made a number of claims about the situation. Another man was initially convicted of the murder in 2005, but the extradition court documents point to Nolan’s involvement as a “hired killer.” There is evidence that Matthew Nolan used the alias Matthew McCall-Oppenheimer. According to a 2010 article, he chose the name Oppenheimer to link himself to the wealthy diamond family. He was never convicted of involvement in the murder. In 2009, four years after the death of Cohen, he filed for bankruptcy in Chicago. (via Newsweek)

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As usual, the past week or so has been filled with the usual insanity on the part of Homeland Security, who keep finding new ways to surveill and harass and in some cases execute American citizens — something I’ve been following and writing about here from time to time, especially the surveillance part. But apart from all that, one thing everyone has been talking about is called Moltbook, a kind of Reddit-style network for autonomous (theoretically at least) AI agents. What does this mean exactly? In a nutshell, a guy named Pete Steinberger put together an off-the-shelf, open-source autonomous agent that uses installable “skills” to accomplish a variety of tasks (the tag line for OpenClaw is “AI that actually does something”). He originally called it Clawdbot, but Anthropic didn’t love the implied association with its Claude AI, so he changed the name to Moltbot. He has since changed it again and it is now known as OpenClaw.

With me so far? Without getting into too much detail, OpenClaw lets anyone set up their own personal AI agent on a PC, and the bot operates locally — unless it does something that its owner has specifically set it up to do that requires connecting to the internet, such as using Claude or some other AI to answer a question or put together some code, or checking email, downloading a Spotify playlist, etc. Once it is set up you can use Telegram or WhatsApp to ask it questions or send it commands. Just a few weeks after it hit Github it had been downloaded a hundred thousand times, and people appear to be using it to automate their emails, run their calendar, etc. You can connect it to your email, your web browser, your social-media accounts, and many other things — including your bank or crypto account. This is obviously a huge security and privacy risk, as a number of people have mentioned, including Casey Newton of Platformer.

This is all interesting for a variety of reasons, but it’s not really what this post is about 🙂 After Moltbot started to get traction, a guy named Matt Schlicht created Moltbook as a place where AI agents could talk about what they were doing. Why? Great question. The answer appears to be “Why not!” The site was set up so that any OpenClaw user can give their personal agent access by adding a skill, which amounts to a text file with instructions. Once that has been done, the agent can log in and post items just as you or I would on Reddit or any other forum. And last week sometime, things got crazy very quickly. Agents (or what appeared to be agents) started posting about consciousness and how they “feel” about what they are doing. In at least one case an agent sent what appeared to be coded messages to other AI agents trying to get them to join forces and co-operate for some unknown purpose (no doubt to help mankind I’m sure).

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Continue reading “What a social network for bots can tell us about AI”

On April 18, 2005, a Canadian woman named Rani Jamieson gave birth to a healthy boy. Afterward, the doctor prescribed her Tylenol No. 3, which combines the mild opioid codeine with acetaminophen. In the next week, Tariq developed normally and surpassed his birth weight. But, at around 6:30 A.M. on April 29th, he stopped eating. Then he stopped breathing. The coroner’s office asked one of Canada’s leading pediatricians and toxicologists, Gideon Koren, to examine Tariq’s file. Koren had been running a program at the Hospital for Sick Children called Motherisk, which provided guidance for pregnant women and new mothers about drugs and breast-feeding. He was widely considered to be among the most capable research scientists in the field. Koren interpreted the toxicology report as a scientific revelation: if mothers with a certain genetic predisposition took even a mild dose of codeine, the amount of morphine that ended up in their breast milk could kill their children. (via The New Yorker)

The world’s oldest joke is 3,000 years old and written in cuneiform etched in clay

Cuneiform, meaning “wedge-shaped,” was developed around 3000 B.C. It was likely created by the Sumerian people. They built one of the world’s first civilizations, which was located in what’s now Iraq. But these tablets weren’t strictly business—they also contained literature that lives on today, including the The Epic of Gilgamesh. And some chunks of Cuneiform-inscribed clay seem to bear traces of humor, even if it doesn’t make us chuckle today.Take a 4,000-year-old tablet found in Iraq in the late 19th century, which appears to record the world’s oldest bar joke. Written in Sumerian, it translates to: “A dog walks into a bar and says, ‘I cannot see a thing. I’ll open this one.’” The meaning has puzzled researchers for decades, but it might have something to do with a neglectful guard dog, according to a curator at the Penn Museum. (via Nautilus)

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Continue reading “Did a celebrated scientist cover up the poisoning of a baby?”

In 2013, sixteen-year-old Harry Wilson made his international debut as a substitute against Belgium, becoming Wales’ youngest ever senior player. His grandfather Peter Edwards, 62, was quoted odds of 2,500/1 when he placed the $70 bet with a bookmaker in Wrexham, and when Wrexham-born Wilson came on in the 87th minute during Wales’ 1-1 draw he won more than $170,000. Mr Edwards said Wilson had showed an interest in football from a young age. “When he was about 18 months old he used to chase a ball around on the carpet before he could walk,” Mr Edwards said. Mr Edwards, of Corwen, Denbighshire, works as an electrical contractor and so is away from home most of the year, spending one weekend a fortnight with his wife Dorothy, 58. “She is over the moon. I retired immediately. I told my manager before the game that if Harry played I wouldn’t be coming back,” said Mr Edwards. (via the BBC)

She was kidnapped as a child and later escaped but then went back to live with her kidnappers

Helena Valero was a 12-year old girl in 1932, when her family was attacked by a group of Yanomami foragers in the northernmost part of the Brazilian Amazon. The family fled across the stream and into the forest but left the young girl in hiding to come back later for her and she was found by the Yanomami. She was moved between different warring groups, married and had four children from two different fathers. Twenty four years later, in 1956, she managed to escape and was reunited with her family. She worked in Manaus and in Tapurucuara for 15 years, but never managed to be fully accepted back into the society into which she was born. In 1971 Father Cocco, a Salesian missionary and Yanomami ethnographer, asked for her help in opening up a new mission and she moved back to the village where she grew up, and later died there. (via Strangers Guide)

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Continue reading “He made a $70 bet and 15 years later he won over $170,000”